
Life Science
Browse all applications for life science
Offering powerful instruments for imaging and analyzing intracellular metabolic pathways, DNA expression, virus penetration and drug localization, CAMECA enables important medical advancements. NanoSIMS is particularly adept for single cell imaging and increasingly used in neurochemistry, other SIMS instruments serve radiation protection, APT is also a powerful tool for atomic-scale analysis of biological interfaces.

Life Science
Radiation Protection: Uranium Diffusion Through Skin (SIMS)
Uranium is a radioactive heavy metal naturally present in earth crust. Internal contamination of nuclear workers by actinides such as uranium may occur either by inhalation, ingestion or penetration through wounds or intact skin, and the SIMS technique is used to assess uranium transfer through the skin. Experiments have been performed in order to characterize uranium bioaccumulation process at skin pig. The results suggest that the stratum corneum is a good defense barrier against the incorporation of the radionuclide into the skin, but can also constitute a reservoir for the diffusion of the radionuclide if no decontamination treatment is applied.

Life Science
Cell Biology: Protein Turnover (NanoSIMS)
The NanoSIMS allows biologists to view and quantify protein turnover and to follow the fate of biomolecules with intra-cellular resolution.

Life Science
Cell Biology: Stem Cell Division Quantification (NanoSIMS)
Experiments involving stable isotope labeling and quantitative Multiple Isotope Mass Spectrometry with the NanoSIMS are conducted in order to test the immortal strand hypothesis.

Life Science
Biominerals: Analysis of Impurities in Tooth (APT)
Atom Probe Tomography allows 3-dimensional atomic-scale analysis of impurities in bones and teeth.

