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Introduction to the NanoSIMS webinars

Friday, January 25, 2019

Starting a new series of NanoSIMS dedicated seminars, we are releasing today two introductory webinars. Click on each link to access our webinar platform. You will need to sign up and can then view the chosen webinar at any time.

  • Introduction to the NanoSIMS. Part 1: Instrumentation principles
    NanoSIMS Product Manager François Horréard presents the basics of dynamic SIMS used in the NanoSIMS instrument. The main components of this unique ion microprobe are then reviewed.

    The original co-axial near-lens extraction and focusing optics permits focusing the primary beam of oxygen or cesium down to 50 nanometer resolution, in DC mode (fast sputtering and high sensitivity). The same optics permits a strong and early extraction of the secondary ions, the beam of which being subsequently focused and shaped in order to optimize transmission of the mass analyzer. Finally, the Mattauch-Herzog magnetic sector mass analyzer allows parallel detection of seven masses, at high mass resolving power and high transmission. Each moveable trolley can receive Electron Multiplier for fast imaging and/or Faraday Cup for high precision isotopic ratios.

  • Introduction to the NanoSIMS. Part 2: Illustration of the main capabilities
    François Horréard illustrates the key characteristics of the unique CAMECA ion microprobe NanoSIMS 50L, using results from scientific publications.

    The NanoSIMS is characterized by an outstanding elemental sensitivity for lateral resolution going down to 50 nanometers. The mass range is illustrated by hydrogen and plutonium imaging. The accessible elements includes lithium often difficult with other techniques. Analysis of electrically insulating samples is possible with thin metal coating and/or charge compensation with an electron flood gun.
    The power of using isotopic tracers to elucidate chemical reactions is illustrated by a study of oxidation path mechanism in a metallic alloy.
    The NanoSIMS can also be used as a depth profilometer with the advantages of small crater analysis, down to µm size.
    In life sciences, the use of stable isotopes is illustrated by a study of symbiosis in coral, based on correlative use of TEM and NanoSIMS. Building pulse-chase experiment enables access to dynamic experiments and measurements. The powerful combination of FISH and NanoSIMS in life science is illustrated in environmental microbiology where the NanoSIMS does not require cultivation for single cell analysis.