February 2018

 
CAMECA 2018 Calendar Competition: SIMS mapping of uranium in the olfactory neuroepithelium

February winning image was submitted by David Suhard, IRSN, France and shows an interesting study of uranium accumulation in the olfactory system and brain in case of exposure via inhalation.

SIMS mapping of uranium in the olfactory neuroepithelium  

Uranium is a radioactive heavy metal naturally present in earth crust. Human activities (extraction, use in nuclear fuel cycles) can also lead to environment dispersal. In the context of occupational exposure via inhalation, experiments have been performed in order to characterize uranium bioaccumulation processes at tissue and cell level in the olfactory system and brain. A) 238U+ ion image,(B) superposed ion images 238U+ (red) and 40Ca+ (green) (C-D) same as A-B at higher magnification. The study was performed with CAMECA IMS 7f.

Intranasal exposure to uranium results in direct transfer to the brain along olfactory nerve bundles. C. Ibanez, D. Suhard, C. Tessier, O. Delissen, P. Lestaevel, I. Dublineau and P. Gourmelon. Neuropathology and Applied Neurobiology 40, 477–488 (2014).